Bone Pain

Record number:

218

Adverse Occurrence type:

MPHO Type:

Estimated frequency:

Common

Alerting signals, symptoms, evidence of occurrence:

Pain, tenderness

Demonstration of imputability or root cause:

Temporal association with GCSF. Definite/probable

Keywords:

G-CSF (granulocyte colony-stimulating factor)

PBSC (peripheral blood stem cells)

References:

Mobilizing stem cells from normal donors: is it possible to improve upon G-CSF?

Recovery and safety profiles of marrow and PBSC donors: experience of the National Marrow Donor Program.

Adverse events among 2408 unrelated donors of peripheral blood stem cells: results of a prospective trial from the National Marrow Donor Program

Peripheral blood stem cell mobilization and apheresis: analysis of adverse events in 94 normal donors

Follow-up of healthy donors receiving granulocyte colony-stimulating factor for peripheral blood progenitor cell mobilization and collection. Results of the Spanish Donor Registry

Mobilized blood cells vs bone marrow harvest: experience compared in 171 donors with particular reference to pain and fatigue

Stem cell mobilisation with 16 microg/kg vs 10 microg/kg of G-CSF for allogeneic transplantation in healthy donors

Treatment of normal donors with rhG-CSF 16 micrograms/kg for mobilization of peripheral blood stem cells and their apheretic collection for allogeneic transplantation

Efficacy and toxicity of a high-dose G-CSF schedule for peripheral blood progenitor cell mobilization in healthy donors

Short and long-term safety of lenograstim administration in healthy peripheral haematopoietic progenitor cell donors: a single centre experience

Harvesting peripheral blood progenitor cells from healthy donors: retrospective comparison of filgrastim and lenograstim

Effects of granulocyte-colony-stimulating factor on potential normal granulocyte donors

Acceptance and feasibility of peripheral stem cell mobilisation compared to bone marrow collection from healthy unrelated donors

Treatment of normal individuals with granulocyte-colony-stimulating factor: donor experiences and the effects on peripheral blood CD34+ cell counts and on the collection of peripheral blood stem cells

Safety and efficacy of hematopoietic stem cell collection from mobilized peripheral blood in unrelated volunteers: 12 years of single-center experience in 3928 donors.

Allogeneic blood progenitor cell collection in normal donors after mobilization with filgrastim: the M.D. Anderson Cancer Center experience

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