Death from metastatic donor-derived ovarian cancer in a male kidney transplant recipient

TitleDeath from metastatic donor-derived ovarian cancer in a male kidney transplant recipient
Publication TypeJournal Article
Year of Publication2009
AuthorsLipshutz GS, Mihara N, Wong R, Wallace WD, Allen-Auerbach M, Dorigo O, Rao PN, Pham PC, Pham PT
JournalAm J Transplant
Volume9
Issue2
Pagination428 - 32
Date PublishedFeb
ISSN1600-6143 (Electronic) 1600-6135 (Linking)
Accession Number19178417
Keywords*Tissue Donors, Adenocarcinoma, Mucinous / *etiology / secondary, Adult, Fatal Outcome, Female, Humans, Kidney Neoplasms / *etiology / secondary, Kidney Transplantation / *adverse effects, Liver Neoplasms / secondary, Lymphatic Metastasis, Male, Middle Aged, Nephrectomy, Ovarian Neoplasms / *etiology / pathology, Tomography, X-Ray Computed
Abstract

Posttransplant malignancy developing in an allograft is an uncommon complication of organ transplantation. The tumor may represent malignant transformation of donor or recipient cells that were previously normal, metastatic malignancy of recipient origin or malignancy transmitted from organ donor to recipient. Establishing the origin of the malignancy is critical to treatment algorithms. It is generally believed allograft removal and immunosuppression withdrawal will lead to resolution of transmitted malignancies in cases where the renal allograft is the origin. We report a male patient who developed metastatic ovarian malignancy secondary to donor transmission.

DOI10.1111/j.1600-6143.2008.02507.x
Notify Library Reference ID914