Transfusion transmitted infections in solid organ transplantation.

TitleTransfusion transmitted infections in solid organ transplantation.
Publication TypeJournal Article
Year of Publication2015
AuthorsMezochow AK, Henry R, Blumberg EA, Kotton CN
JournalAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons// // Am J Transplant
Pagination547 - 54
Date Published2015//
ISBN Number1600-6143
Other Numbers100968638
Keywords*Blood Transfusion/ae [Adverse Effects], *Organ Transplantation, *Virus Diseases/ep [Epidemiology], *Virus Diseases/tm [Transmission], Cytomegalovirus, Cytomegalovirus Infections/ep [Epidemiology], Cytomegalovirus Infections/tm [Transmission], Humans, Prevalence, Retrospective Studies, Risk Factors, Virus Diseases/vi [Virology], West Nile Fever/ep [Epidemiology], West Nile Fever/tm [Transmission], West Nile virus

While the risk of infectious disease transmission through blood transfusion has been greatly reduced as a result of improved screening methods, transfusion-transmissible infections remain a concern for transplant recipients, especially those receiving multiple transfusions. Although transfusion and transplant recipients are at risk for similar infections, the current reporting requirements for infections transmitted by transfusions and organ transplantation vary greatly and remain distinctly separate with no communication between reporting systems. This article reviews 23 past reports of transfusion-transmitted infections in organ recipients acquired through transfusions. While cytomegalovirus was a major focus of such reports in the 1980s, more recent reports have focused on West Nile virus transmission. Additionally, this article highlights challenges in determining transfusion-transmitted infection risk in transplant recipients related to the current reporting systems. © Copyright 2015 The American Society of Transplantation and the American Society of Transplant Surgeons.

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