Leukocytosis

Record number:

516

Adverse Occurrence type:

MPHO Type:

Estimated frequency:

Common

Time to detection:

During days of injections

Alerting signals, symptoms, evidence of occurrence:

Leukocytosis

Demonstration of imputability or root cause:

Temporal association with GCSF. Definite.

Imputability grade:

3 Definite/Certain/Proven

Keywords:

G-CSF (granulocyte colony-stimulating factor)

PBSC (peripheral blood stem cells)

References:

Adverse events among 2408 unrelated donors of peripheral blood stem cells: results of a prospective trial from the National Marrow Donor Program

Follow-up of healthy donors receiving granulocyte colony-stimulating factor for peripheral blood progenitor cell mobilization and collection. Results of the Spanish Donor Registry

Treatment of normal donors with rhG-CSF 16 micrograms/kg for mobilization of peripheral blood stem cells and their apheretic collection for allogeneic transplantation

Efficacy and toxicity of a high-dose G-CSF schedule for peripheral blood progenitor cell mobilization in healthy donors

Effects of granulocyte-colony-stimulating factor on potential normal granulocyte donors

Peripheral blood stem cell apheresis for allogeneic transplants: Ibni Sina experience

Recombinant human interleukin-3 (rhIL-3) enhances the mobilization of peripheral blood progenitor cells by recombinant human granulocyte colony-stimulating factor (rhG-CSF) in normal volunteers

Treatment of normal individuals with granulocyte-colony-stimulating factor: donor experiences and the effects on peripheral blood CD34+ cell counts and on the collection of peripheral blood stem cells

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