Potential donors are screened for infectious risks on the basis of national standards and regulations. A first step in screening donors is a thorough medical and social history (including sexual history and other behavioural risks, such as injectable drug use) as well as physical examination by the team during collection/procurement to detect any unknown infections or malignancies. This initial evaluation, including travel, animal and environmental exposure history, may reveal risks for current or active infections that should be addressed prior to donation of MPHO. Any such screening must be consistent with the requirements of the screening process as well as local and national policies and regulations.
