Tuberculosis transmitted through transplantation

TitleTuberculosis transmitted through transplantation
Publication TypeJournal Article
Year of Publication2001
AuthorsGraham JC, Kearns AM, Magee JG, El-Sheikh MF, Hudson M, Manas D, Gould FK, Orr KE, Freeman R
JournalJ Infect
Pagination251 - 4
Date PublishedNov
ISSN0163-4453 (Print) 0163-4453 (Linking)
Accession Number11869064
KeywordsAdult, Cadaver, Cross Infection / diagnosis / transmission, Female, Humans, Kidney Transplantation / *adverse effects, Liver Transplantation / *adverse effects, Male, Middle Aged, Mycobacterium tuberculosis / genetics / *isolation & purification, Polymerase Chain Reaction, Risk Factors, Tuberculosis / *diagnosis / *transmission, Tuberculosis, Hepatic / diagnosis / transmission, Tuberculosis, Renal / diagnosis / transmission

Tuberculosis in solid organ transplant recipients is associated with relatively high morbidity and mortality and is often extra-pulmonary. Reactivation of dormant infection is the usual mode of acquisition with donor and nosocomial transmission occurring infrequently. We report two cases of probable donor transmitted extra-pulmonary infection where both isolates of Mycobacterium tuberculosis proved to be indistinguishable using hemi-nested inverse PCR of the IS 6110 region.

DOI10.1053/jinf.2000.0879 S0163-4453(00)90879-X [pii]
Notify Library Reference ID604

Related Incidents