Rocky mountain spotted fever caused by blood transfusion.

TitleRocky mountain spotted fever caused by blood transfusion.
Publication TypeJournal Article
Year of Publication1978
AuthorsWells GM, Woodward TE, Fiset P, Hornick RB
JournalJAMA
Volume239
Issue26
Pagination2763 - 5
Date Published1978
ISBN Number0098-7484
Other Numbers7501160
Keywords*Blood Transfusion/ae [Adverse Effects], *Rocky Mountain Spotted Fever/et [Etiology], Aged, Blood Donors, Blood/mi [Microbiology], Humans, Male, Middle Aged, Rickettsia rickettsii/ip [Isolation & Purification], Rocky Mountain Spotted Fever/tm [Transmission]
Abstract

Transfusion of 500 ml of blood, contributed by a donor three days before the onset of Rocky Mountain spotted fever and refrigerated for nine days, caused this disease in the recipient. The blood donor died of Rocky Mountain spotted fever after six days; rickettsia were identified in various tissues by immunofluorescence techniques. The recipient of the blood became mildly ill and recovered fully; specific antibiotic treatment was initiated on the fourth day of illness. Diagnosis of Rocky Mountain spotted fever was confirmed in the recipient by positive serologic reactions and isolation of Rickettsia rickettsii from blood after inoculation in animals and tissue culture.

Notify Library Reference ID4439

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