A delayed hemolytic transfusion reaction due to anti-Cob.

TitleA delayed hemolytic transfusion reaction due to anti-Cob.
Publication TypeJournal Article
Year of Publication1985
AuthorsSquires JE, Larison PJ, Charles WT, Milner PF
Pagination137 - 9
Date Published1985
ISBN Number0041-1132
Other Numberswdn, 0417360
Keywords*Anemia, Hemolytic/et [Etiology], *Blood Group Antigens/im [Immunology], *Blood Transfusion/ae [Adverse Effects], *Isoantibodies/ph [Physiology], Adult, Anemia, Hemolytic/bl [Blood], Anemia, Sickle Cell/co [Complications], Anemia, Sickle Cell/th [Therapy], Female, Humans, Time Factors

A delayed hemolytic transfusion reaction precipitated by anti-Cob is described in a multiple transfused primigravida woman with sickle-cell disease. Sixteen days after the prophylactic transfusion of the first of 4 units of red cells, she experienced a fall in hemoglobin concentration accompanied by a newly positive antibody screen and direct antiglobulin test. Anti-Cob was identified both in the patient's serum and in an eluate prepared from her red cells.

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