|Acute intravascular haemolysis associated with high dose immunoglobulin after bone marrow transplantation for acute myelogenous leukemia
|Year of Publication
|Rovelli A., D'Angelo P., Balduzzi A., Borzini P., Biondi A., Uderzo C.
|Leukemia and Lymphoma
|autoimmune thrombocytopenia, Bone Marrow Transplantation, High dose immunoglobulin, intravascular haemolysis
A 12-year-old boy developed persistent thrombocytopenia after undergoing bone marrow transplantation for acute myelogenous leukemia. High doses of intravenous immunoglobulins were used to treat overt hemorrhage and a sudden intravascular hemolysis occurred. The serologic findings point to an acute hemolysis secondary to the presence of isohemoagglutinins in the intravenous immunoglobulin preparations.
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