Acute intravascular haemolysis associated with high dose immunoglobulin after bone marrow transplantation for acute myelogenous leukemia

TitleAcute intravascular haemolysis associated with high dose immunoglobulin after bone marrow transplantation for acute myelogenous leukemia
Publication TypeJournal Article
Year of Publication1991
AuthorsRovelli A., D'Angelo P., Balduzzi A., Borzini P., Biondi A., Uderzo C.
JournalLeukemia and Lymphoma
Volume5
Pagination71-74
Keywordsautoimmune thrombocytopenia, Bone Marrow Transplantation, High dose immunoglobulin, intravascular haemolysis
Abstract
A 12-year-old boy developed persistent thrombocytopenia after undergoing bone marrow transplantation for acute myelogenous leukemia. High doses of intravenous immunoglobulins were used to treat overt hemorrhage and a sudden intravascular hemolysis occurred. The serologic findings point to an acute hemolysis secondary to the presence of isohemoagglutinins in the intravenous immunoglobulin preparations.

 

DOI10.3109/10428199109068107
Notify Library Reference ID4405

Related Incidents