Organ transplantation from a donor colonized with a multidrug-resistant organism: a case report.

TitleOrgan transplantation from a donor colonized with a multidrug-resistant organism: a case report.
Publication TypeJournal Article
Year of Publication2012
AuthorsGoldberg E., Bishara J., Lev S., Singer P., Cohen J.
Journal//Transpl Infect Dis
Volume14
Issue3
Pagination296 - 299
Date Published2012
ISBN Number1398-2273
Other Numbersd1d, 100883688
Keywordscarbapenem-resistant Klebsiella, multidrug-resistant organisms, solid organ transplantation
Abstract

colon; The number of intensive care unit patients with infections caused by multidrug-resistant organisms is increasing in most developed countries. We report the case of a deceased multiorgan donor, who was an asymptomatic carrier of carbapenem-resistant Klebsiella pneumoniae (CR-KP) in the respiratory tract, a condition that was not diagnosed before organ harvesting and transplantation. The outcome of the 2 kidney recipients, the liver recipient, and 1 of the lung recipients was uneventful; in particular, no evidence of infection transmission or adverse graft outcomes was noted. The other lung recipient had a complicated postoperative course and, 4 weeks post transplantation, he developed a bacteremic pneumonia with CR-KP from which he subsequently died. These results suggest that, in well defined conditions, organs from donors who are CR-KP positive may be considered for transplantation., Copyright (C) 2012 Blackwell Publishing Ltd.

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