Acquired toxoplasmic retinochoroiditis after platelet transfusions.

TitleAcquired toxoplasmic retinochoroiditis after platelet transfusions.
Publication TypeJournal Article
Year of Publication1989
AuthorsNelson JC, Kauffmann DJ, Ciavarella D, Senisi WJ
JournalAnnals of ophthalmology//Ann Ophthalmol
Pagination253 - 4
Date Published1989
ISBN Number0003-4886
Other Numbers5pa, 0210137
Keywords*Blood Transfusion/ae [Adverse Effects], *Chorioretinitis/et [Etiology], *Platelet Transfusion, *Toxoplasmosis, Adrenal Cortex Hormones, Female, Fluorescein Angiography, Humans, Macular Edema/co [Complications], Middle Aged, Sulfamethoxazole/ae [Adverse Effects], Thrombocytopenia/ci [Chemically Induced], Time Factors, Visual Acuity

We present a rare well-documented case of acquired toxoplasmic retinochoroiditis transmitted by platelet transfusion. A 52-year-old woman developed severe thrombocytopenia shortly after receiving a sulfamethoxazole-containing antibiotic. This episode was treated with platelet transfusions and a three-day course of corticosteroids. Thirteen days later, she developed an acute febrile illness typical of the typhus-like form of toxoplasmosis. Fifty-six days later, while still taking corticosteroids for recurrent immune thrombocytopenia, she developed an acute macular retinochoroiditis OD. Serology showed recently acquired toxoplasmosis. Epidemiologic investigation revealed no possible source for the toxoplasmosis other than the platelet transfusion.

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