Record number: 
Adverse Occurrence type: 
MPHO Type: 
Time to detection: 
13 days
Alerting signals, symptoms, evidence of occurrence: 
Thirteen days after platelet transfusions, patient developed rigors, fever and diffuse erythematous papules over most of the body including the dorsum of the hands sparing palms and soles. Sixty-nine days after the transfusions, and 56 days after onset of fever, developed loss of visual acuity and an acute macular retinochoroiditis.
Demonstration of imputability or root cause: 
Serology showed recently acquired toxoplasmosis. Epidemiologic investigation revealed no possible source for the toxoplasmosis other than the platelet transfusion. Three donors had IgG anti-toxoplasma titers of 1/64 - 1/512.
Imputability grade: 
2 Probable
Suggest references: 
Nelson, J.C., Kauffmann, D.J.H., Ciavarella, D. and Sensis, W.J. (1989). Acquired toxoplasmic retinochoroiditis after platelet transfusions. Ann Ophthalmol 21:253-254