Ecthyma gangrenosum in a kidney transplant recipient with Pseudomonas septicemia

TitleEcthyma gangrenosum in a kidney transplant recipient with Pseudomonas septicemia
Publication TypeJournal Article
Year of Publication1986
AuthorsCollini FJ, Spees EK, Munster A, Dufresne C, Millan J
JournalThe American journal of medicine
Pagination729 - 34
Date PublishedApr
Type of ArticleCase Reports
ISSN0002-9343 (Print) 0002-9343 (Linking)
Accession Number3515936
Keywords*Kidney Transplantation, Adult, Ecthyma / drug therapy / *pathology, Gangrene / drug therapy / pathology, Humans, Male, Postoperative Complications / drug therapy / pathology, Pseudomonas Infections / drug therapy / *pathology, Sepsis / drug therapy / pathology

This report describes a renal transplant recipient in whom Pseudomonas septicemia and ecthyma gangrenosum developed within days of renal transplantation. Microscopic skin sections showed perivascular bacillary invasion. Pseudomonas organisms were cultured and microscopically visualized in sections from the transplanted kidney. Although cultures from the donor kidney preservation perfusate fluid showed no growth, Pseudomonas aeruginosa was found in the recipient's urine, blood, and peritoneal fluid. The recipient's course was complicated by septic shock, cardiopulmonary arrest, coma, and extensive skin lesions; but his condition improved with appropriate antibiotic therapy, wound debridement, and an aggressive rehabilitative program. He is now a candidate for retransplantation. This is the first known case of ecthyma gangrenosum in a renal transplant recipient.

Alternate JournalAm J Med
Notify Library Reference ID365

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