Kaposi's sarcoma developing in a liver graft

TitleKaposi's sarcoma developing in a liver graft
Publication TypeJournal Article
Year of Publication1996
AuthorsColina F, Lopez-Rios F, Lumbreras C, Martinez-Laso J, Garcia IG, Moreno-Gonzalez E
Pagination1779 - 1781
Date PublishedJun 27
ISSN0041-1337; 0041-1337
Accession NumberPMID: 8685961
KeywordsHumans, Immunosuppressive Agents / adverse effects, Liver Neoplasms / etiology / pathology, Liver Transplantation / adverse effects, Male, Middle Aged, Sarcoma, Kaposi / etiology

The case reported herein involved a patient who developed Kaposi's sarcoma (KS) in the liver graft, with severe liver disfunction and eventually the patient's death. This patient is our only KS case among the 7 neoplasias arising de novo (6 lymphoproliferative syndromes) in a series of 402 liver transplants (382 immunosuppressed with cyclosporine and prednisolone and 20 with FK-506 and prednisolone). The anatomic distribution of the KS in the autopsy study, and the HLA haplotypes typed in the donor and in the recipient, suggest that the KS arose in the stromal endothelial cells of the donor liver.

Alternate JournalTransplantation
Notify Library Reference ID1688