Case Report: Kaposi’s sarcoma after liver transplant (1996)

Record number:

259

Adverse Occurrence type:

MPHO Type:

Estimated frequency:

- Most recent risk assessment for non-melanoma skin cancer (Council of Europe, 2025): Non-melanoma skin cancer diagnosed during donor procurement or in the donor history: Basal cell and squamous cell carcinoma of the skin are considered minimal risk due to very rare metastases. Kaposi sarcoma, Merkel cell carcinoma and skin sarcoma are considered an unacceptable risk.

Time to detection:

4 months

Alerting signals, symptoms, evidence of occurrence:

About 130 days after tx, severe liver disfunction and patient´s death due to multiorgan failure. Liver graft biopsy at autopsy revealed a KS.

Demonstration of imputability or root cause:

The anatomic distribution of the KS in the autopsy study, and the HLA haplotypes typed in the donor and in the recipient, suggested that the KS arose in the stromal endothelial cells of the donor liver.

Imputability grade:

3 Definite/Certain/Proven

Groups audience:

Keywords: