Broncholith caused by donor-acquired histoplasmosis in a lung transplant recipient

TitleBroncholith caused by donor-acquired histoplasmosis in a lung transplant recipient
Publication TypeJournal Article
Year of Publication2007
AuthorsShah SS, Karnak D, Shah SN, Budev M, Machuzak M, Gildea TR, Mehta AC
JournalJ Heart Lung Transplant
Volume26
Issue4
Pagination407 - 10
Date PublishedApr
ISSN1557-3117 (Electronic) 1053-2498 (Linking)
Accession Number17403485
Keywords*Tissue Donors, Adult, Bronchi / pathology, Bronchial Diseases / *microbiology / pathology / radiography, Histoplasmosis / *complications / transmission, Humans, Lithiasis / *microbiology / pathology / radiography, Lung Diseases, Fungal / *complications, Lung Transplantation / *adverse effects, Male, Radiography, Thoracic, Time Factors, Tomography, X-Ray Computed
Abstract

A broncholith is a calcified lymph node that erodes into and partially or completely obstructs the bronchial lumen. The natural history of broncholiths is poorly understood. They are frequently encountered in residents of areas that are endemic for Histoplasma capsulatum and Mycobacterium tuberculum. We report the first case of a broncholith in which the fungus Histoplasma capsulatum was transferred from a donor to a lung transplant (LTx) recipient. Our report highlights the time course of broncholith development and its successful management. We suspect that broncholithiasis and transmission of Histoplasma capsulatum from a donor to the recipient are under-reported in the LTx literature. We hypothesize that histoplasmosis can be transmitted from the donor to the recipient and the duration in the formation of calcification of the lymph node or the broncholith can be anywhere from 2 to 10 months.

DOI10.1016/j.healun.2007.01.014
Short TitleBroncholith caused by donor-acquired histoplasmosis in a lung transplant recipient
Notify Library Reference ID1393

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