Cephalosporium endophthalmitis following penetrating keratoplasty

TitleCephalosporium endophthalmitis following penetrating keratoplasty
Publication TypeJournal Article
Year of Publication1979
AuthorsRao GN, Aquavella JV
JournalOphthalmic Surg
Pagination34 - 7
Date PublishedFeb
ISSN0022-023X (Print) 0022-023X (Linking)
Accession Number370708
Keywords*Corneal Transplantation, Acremonium / *isolation & purification, Aged, Antifungal Agents / therapeutic use, Cataract Extraction, Descemet Membrane, Endophthalmitis / complications / *microbiology / therapy, Humans, Keratitis, Dendritic / surgery, Male, Mycoses / *complications, Ophthalmologic Surgical Procedures, Postoperative Complications, Transplantation, Homologous

A 69-year-old male with chronic herpes simplex keratitis underwent penetrating keratoplasty, using cryopreserved tissue. Seven weeks postoperatively the patient developed cephalosporium endophthalmitis. Intensive medical and surgical therapy was unsuccessful and the eye had to be enucleated within three weeks. Cephalosporium species are isolated more often in intraocular infection than from corneal ulceration. Although favorable response to Amphotericin-B and Primaricin has been reported, the final outcome has been unfavorable in most of these cases.

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Notify Library Reference ID1299

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