Adverse Occurrence type:
Time to detection:
Alerting signals, symptoms, evidence of occurrence:
A 69-year-old male with chronic herpes simplex keratitis underwent penetrating keratoplasty, using cryopreserved tissue. Seven weeks postoperatively the patient developed cephalosporium endophthalmitis and corneal ulceration. Treatment failed and eye enucleated.
Demonstration of imputability or root cause:
Unproven No proof of donor tissue infection or transmission.