Visceral leishmaniasis after orthotopic liver transplantation: impact of persistent splenomegaly.

TitleVisceral leishmaniasis after orthotopic liver transplantation: impact of persistent splenomegaly.
Publication TypeJournal Article
Year of Publication1993
AuthorsHorber FF, Lerut JP, Reichen J, Zimmermann A, Jaeger P, Malinverni R
JournalTransplant international : official journal of the European Society for Organ Transplantation//Transpl Int
Volume6
Issue1
Pagination55 - 7
Date Published1993
ISBN Number0934-0874
Other Numbersady, 8908516
Keywords*Leishmaniasis, Visceral/et [Etiology], *Liver Diseases, Parasitic/et [Etiology], *Liver Transplantation/ae [Adverse Effects], Female, Humans, Leishmaniasis, Visceral/pa [Pathology], Liver Diseases, Parasitic/pa [Pathology], Liver Transplantation/pa [Pathology], Middle Aged
Abstract

Visceral leishmaniasis was observed in a 50-year-old female liver transplant recipient 1 year following transplantation. Signs of active infection were low-grade fever, pancytopenia, persistent splenomegaly, positive cultures for leishmania in liver and bone marrow biopsy specimens, and newly positive leishmania serology. Following sequential therapy with pentavalent antimony and amphotericin B, blood values improved massively, bone marrow cultures became negative, and leishmania serology decreased. Secondary prophylaxis with fluconazole was instituted and the patient remains without signs of active infection 1 year after successful therapy.
Notify Library Reference ID4337

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