Atopy/allergy

Record number:

1098

Adverse Occurrence type:

Hypersensitivity, Allergy

MPHO Type:

Estimated frequency:

Known. Not uncommon

Time to detection:

months - years

Alerting signals, symptoms, evidence of occurrence:

Food allergy. Asthma. Drug allergy. Rhinitis

Demonstration of imputability or root cause:

No allergy prior to transplant. Donor has history of atopy/allergy. Raised serum IgE, positive radioallergosorbent tests.

Keywords:

IgE (immunoglobulin E)

RAST (radioallergosorbent test)

References:

Atopy after bone marrow transplantation.

Transfer of atopy following bone marrow transplantation

Total and allergen-specific IgE in relation to allergic response pattern following bone marrow transplantation.

Transfer of allergen-specific IgE-mediated hypersensitivity with allogeneic bone marrow transplantation.

Is allergic disease curable or transferable with allogeneic hematopoietic cell transplantation?.

Suggest references:

Tucker, J, et al 1986. Atopy after bone marrow transplantation. Br Med J 290:116-7; Bellou, A. et al 1997. Transfer of atopy following bone marrow transplantation. Ann Allergy Asthma Immunol 78:513-6; Walker, SA, et al, 1986. Total and allergen-specific IgE in relation to allergic response pattern following bone marrow transplantation. Clin Exp Immunol 66:633-9; Agosti, JM, et al, 1988.Transfer of allergen-specific IgE-mediated hypersensitivity with allogeneic bone marrow transplantation. N Engl J Med 319:1623-8; Khan, f, et al, 2009. Is allergic disease curable or transferable with allogeneic hematopoietic cell transplantation? Blood 113:279-90.