Generalized seizure

Record number:

497

Adverse Occurrence type:

MPHO Type:

Estimated frequency:

Uncommon

Alerting signals, symptoms, evidence of occurrence:

Abnormal movements, aura during injections or apheresis

Demonstration of imputability or root cause:

Temporal association with GCSF. Definite/probable

Keywords:

abnormal movements

G-CSF (granulocyte colony-stimulating factor)

PBSC (peripheral blood stem cells)

allogeneic unrelated

References:

Allogeneic blood progenitor cell collection in normal donors after mobilization with filgrastim: the M.D. Anderson Cancer Center experience

Severe events in donors after allogeneic hematopoietic stem cell donation

Adverse events among 2408 unrelated donors of peripheral blood stem cells: results of a prospective trial from the National Marrow Donor Program

World Marrow Donor Association. SEAR Registry, 12th ed.