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    • 1 INTRODUCTION
    • 2 THE V&S CHAIN FOR MPHOs
    • 3 VIGILANCE AND SURVEILLANCE: HISTORY AND BASIC ELEMENTS
    • 4 MEDICAL PRODUCTS OF HUMAN ORIGIN (MPHO) - DONATION AND ETHICS
    • ANNEX 1. Notify Library - MPHO type taxonomy
    • 5 TOWARDS A GLOBAL GOVERNANCE OF MPHO
    • 6 THE V&S SYSTEM IS PRIMARILY A RESPONSIBILITY FOR HEALTH AUTHORITIES
    • 7 ORGANIZATION FOR A COMPREHENSIVE - VIGILANCE & SURVEILLANCE SYSTEM
    • 8 VIGILANCE & SURVEILLANCE - RECOGNITION RELIES ON HEALTH CARE STAFF
    • 9 INVESTIGATING OCCURRENCES THAT COULD CAUSE HARM - LEARNING FROM ERRORS
    • 10 PROJECT NOTIFY
    • 11 THE NOTIFY DATABASE - LEARNING FROM VIGILANCE
    • 12 RISKS ASSOCIATED WITH LIVING DONATION
    • 13 HARM TO RECIPIENT - INFECTIONS
    • 14 HARM TO RECIPIENT - NON INFECTIOUS BLOOD TRANSFUSION REACTIONS
    • 15 HARM TO RECIPIENTS - MALIGNANCY
    • 16 HARM TO RECIPIENTS - GENETIC TRANSMISSIONS - HPC
    • 17 HARM TO RECIPIENTS - GENETIC TRANSMISSIONS - gamets and embryos
    • 18 CHARACTERISTICS, HANDLING AND CLINICAL ERRORS
    • 19 TRACEABILITY, AN ABSOLUTE PRE-REQUISITE FOR MPHO SAFETY
    • ANNEX 2. Notify Library - Adverse occurrence type taxonomy
    • REFERENCES
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Home / Harm to a Donor / Drug related reactions / GCSF-related / Fever

Fever

Record number: 
494
Adverse Occurrence type: 
GCSF-related
MPHO Type: 
Apheresis
Estimated frequency: 
Common
Alerting signals, symptoms, evidence of occurrence: 
Fever during days of injections
Demonstration of imputability or root cause: 
Definite/probable. Temporal association with GCSF.
Keywords: 
fever
G-CSF (granulocyte colony-stimulating factor)
injections
donor reaction
PBSC (peripheral blood stem cells)
apheresis
allogeneic
References: 
Adverse events among 2408 unrelated donors of peripheral blood stem cells: results of a prospective trial from the National Marrow Donor Program
Short and long-term safety of lenograstim administration in healthy peripheral haematopoietic progenitor cell donors: a single centre experience
Harvesting peripheral blood progenitor cells from healthy donors: retrospective comparison of filgrastim and lenograstim
Suggest references: 
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The cases, bibliography and associated comments included in this website and database have been provided by experts worldwide and reviewed by voluntary editorial working groups. The data and information is not guaranteed to be complete or to be fully up to date at any particular moment and it reflects the knowledge and views of the experts participating, not those of the World Health Organisation or the Italian National Transplant Centre.