Record number:
140
Adverse Occurrence type:
MPHO Type:
Estimated frequency:
Most recent risk assessment for leukemia, lymphoma and plasmacytoma (Council of Europe, 2022) (refers typically to solid organ transplant):
Leukaemia, lymphoma and plasmacytoma diagnosed during donor procurement: These cancers are classified as an unacceptable risk for organ donation. Leukaemia, lymphoma and plasmacytoma in the donor history: Active (acute or chronic) leukaemia, lymphoma and plasmacytoma are an unacceptable risk for organ donation. Treated acute leukaemia and lymphoma after a definite disease-free interval of 10 years may be considered for organ donation with an assumed high risk for transmission.
Alerting signals, symptoms, evidence of occurrence:
Donated femoral head for bone grafting, would have been transplanted but by histological examination resulted in discard. Not a routine procedure at the time.
Demonstration of imputability or root cause:
Histological examination of femoral head
References:
Suggest new keywords:
Malignancy
Suggest references:
[1127] Palmer, S.H.; Gibbons, C.L.; Athanasou, N.A. The pathology of bone allograft J Bone Joint Surg Br 1999; 81 (2) :333 - 5