Status:
Ready to upload
Record number:
2128
Adverse Occurrence type:
MPHO Type:
Estimated frequency:
The estimated frequency of chylous ascites post laparoscopic living donor nefrectomy in a cohort of 1563 (Dale, 2018) was 0,19%, in the case report by Seth (2019) 1 in 2100. In literature range between 0-6% are reported, higher percentage linked to learning curve in small cohort.
Time to detection:
First symptoms were recorded 1-2 weeks post laparoscopic living donor nefrectomy. In all cases paracentesis of intra abdominal fluid was done, and analysis confirmed chylous ascites (presence of high percentage of lymphocytes and triglycerides).
Alerting signals, symptoms, evidence of occurrence:
All donors had abdominal complaints. All donors had donated a left kidney (the majority of kidney donations are left-sided).
Demonstration of imputability or root cause:
Chylous ascites is a rare complication after living donor nefrectomy. In all cases paracentesis of intra abdominal fluid was done, and analysis confirmed chylous ascites (presence of high percentage of lymphocytes and triglycerides).
Imputability grade:
3 Definite/Certain/Proven
Groups audience:
References:
Reference attachment:
Suggest references:
1) Dale et al. Clin Transplant. 2019 Mar;33(3):e13483
2) Seth et al. ransplantation. 2019 Apr;103(4):e74-e78
Expert comments for publication:
Although the incidence of chylous ascites post living donor nefrectomy is very low, it is important to mention to the donor, since the impact of the complication is major and time consuming. More experienced centers see this complication less often.