Coccidioides immitis

Record number: 
654
Adverse Occurrence type: 
Coccidioides
MPHO Type: 
Multiple types or not specified
Alerting signals, symptoms, evidence of occurrence: 
This study uses DNA sequencing to show that 3 recipients of organs from the same donor had identical markers. Donor tissue was not available for sequencing to show identical Coccidioides immitis but a blood sample showed IgM antibosies to Coccidioides immitis. No clinical details of donor or recipients are presented.  The donor and recipients lived in an endemic area, Los Angeles, California.
Demonstration of imputability or root cause: 
Level 3. Likely. Same organism in 3 recipients and in donor infection
Imputability grade: 
2 Probable
Keywords: 
coccidioidomycosis
organ transplantation
donor infection
fungal infection
DNA sequencing
Coccidioides immitis
References: 
Next-generation sequencing of Coccidioides immitis isolated during cluster investigation.
Donor-derived fungal infections in transplant patients
Suggest references: 
Donor-derived fungal infections in transplant patients, Roy, M., Park B. J., and Chiller T. M. , Curr Fungal Infect Rep, Volume 4, p.219 - 228, (2010)