Rabies virus

Record number: 
597
Adverse Occurrence type: 
MPHO Type: 
Estimated frequency: 
3 of 6 recipients ( 0 of 2 corneas)
Time to detection: 
45 days
Alerting signals, symptoms, evidence of occurrence: 
Altered mental status,respiratory distress and fever
Demonstration of imputability or root cause: 
Certain. Uncommon disease in donor and 3 recipients (liver, kidneys, pancreas).  In the course of a routine look-back procedure on day 45 after transplantation, similarity of symptoms of recipient 4 with those of the donor was notified (altered mental status,respiratory distress and fever) . Similar findings were also confirmed in recipients 5 and 6. Rabies virus transmitted to lung, kidney and kidney/pancreas but not liver recipient (had rabies vaccine many years previously)
Imputability grade: 
3 Definite/Certain/Proven
Suggest references: 
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