Lymphocytic choriomeningitis virus (LCMV)

Record number: 
590
MPHO Type: 
Estimated frequency: 
As of Aug 2012: US 4 donors (14 recipients) with 11 deaths
Time to detection: 
10 days
Alerting signals, symptoms, evidence of occurrence: 
Pneumonia, hepatitis,  dyspnea, abdominal pain, nausea and vomiting;
Demonstration of imputability or root cause: 
Certain. Donor and recipients positive by virus culture and reverse transcription polymerase chain reaction [PCR], with identical sequences of the 396-bp fragment of the large segment of the virus. Presence of IgM and LCMV antigen positve immunocytochemistry.
Imputability grade: 
3 Definite/Certain/Proven
Suggest references: 
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