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    • 6 THE V&S SYSTEM IS PRIMARILY A RESPONSIBILITY FOR HEALTH AUTHORITIES
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    • 15 HARM TO RECIPIENTS - MALIGNANCY
    • 16 HARM TO RECIPIENTS - GENETIC TRANSMISSIONS - HPC
    • 17 HARM TO RECIPIENTS - GENETIC TRANSMISSIONS - gamets and embryos
    • 18 CHARACTERISTICS, HANDLING AND CLINICAL ERRORS
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    • ANNEX 2. Notify Library - Adverse occurrence type taxonomy
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Home / Harm to a Donor / Drug related reactions / GCSF-related / Generalized seizure

Generalized seizure

Record number: 
497
Adverse Occurrence type: 
GCSF-related
MPHO Type: 
Apheresis
Estimated frequency: 
Uncommon
Alerting signals, symptoms, evidence of occurrence: 
Abnormal movements, aura during injections or apheresis
Demonstration of imputability or root cause: 
Temporal association with GCSF. Definite/probable
Keywords: 
abnormal movements
aura
G-CSF (granulocyte colony-stimulating factor)
PBSC (peripheral blood stem cells)
apheresis
donor reaction
seizures
allogeneic
allogeneic unrelated
References: 
Allogeneic blood progenitor cell collection in normal donors after mobilization with filgrastim: the M.D. Anderson Cancer Center experience
Severe events in donors after allogeneic hematopoietic stem cell donation
Adverse events among 2408 unrelated donors of peripheral blood stem cells: results of a prospective trial from the National Marrow Donor Program
World Marrow Donor Association. SEAR Registry, 12th ed.
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Disclaimer

The cases, bibliography and associated comments included in this website and database have been provided by experts worldwide and reviewed by voluntary editorial working groups. The data and information is not guaranteed to be complete or to be fully up to date at any particular moment and it reflects the knowledge and views of the experts participating, not those of the World Health Organisation or the Italian National Transplant Centre.