Record number:
308
Adverse Occurrence type:
MPHO Type:
Estimated frequency:
Most recent risk assessment (Council of Europe, 2022): Oesophageal, gastric, pancreatic, liver and biliary cancers diagnosed during donor procurement : These tumours are classified as unacceptable risk. Oesophageal, gastric, pancreatic, liver and biliary cancers in the donor history: Treated tumours of these kinds in the donor history are classified as high risk due to their aggressive behaviour. Risk may decrease for early stages after curative therapy, with recurrence-free time > 5 years and with increasing probability of cure, especially in cases of long-term survivors
Time to detection:
Not given
Alerting signals, symptoms, evidence of occurrence:
Not specified
Demonstration of imputability or root cause:
Evaluated by OPTN/UNOS Disease Transmission Advisory Committee (DTAC) as confirmed transmission. (Two donors transmitted disease to 3 recipients).
Imputability grade:
3 Definite/Certain/Proven
Groups audience:
Keywords:
Suggest new keywords:
Registry series
malignancy
Reference attachment:
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Expert comments for publication:
Information listed as part of UNOS/DTAC update of transmitted infectious and neoplastic diseases (2011). No specific information given regarding individual cases. DTAC adjudicates cases as probable or proven before reporting them as transmission events.