Case report: T-cell lymphoma (2008)

Record number: 
Adverse Occurrence type: 
MPHO Type: 
Estimated frequency: 
Most recent risk assessment for CNS lymphoma (Council of Europe, 2022): Organs from donors with primary cerebral lymphomas have an unacceptable risk for tumour transmission and should not be considered for transplantation.
Time to detection: 
40 days
Alerting signals, symptoms, evidence of occurrence: 
Continued pancreatitis despite treatment of rejection; CT showed pancreatic phlegmon, exploration showed firm pancreas with "pseudocyst"; Underwent pancreatectomy following notification of donor CNS lymphoma diagnosed by autopsy. Pancreas and later peritoneum, mediastinum shown to be involved.
Demonstration of imputability or root cause: 
FISH for XY chromosomes. T-cell receptor clonal studies
Imputability grade: 
3 Definite/Certain/Proven
Groups audience: 
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Case report
Kidney transplant
Pancreas transplant
Heart transplant
Deceased donor
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