Status:
Ready to upload
Record number:
1333
Adverse Occurrence type:
MPHO Type:
Estimated frequency:
Under dispute but approximately 350/100,000 platelets
Time to detection:
45 minutes
Alerting signals, symptoms, evidence of occurrence:
Fever of 40°C, rigors, persistent hypotension unresponsive to fluids, WBC 42,000.
Demonstration of imputability or root cause:
Culture of Streptococcus bovis in the platelet bag, sealed tubing of platelets, and 4 blood cultures from the recipient.
Imputability grade:
3 Definite/Certain/Proven
Groups audience:
Keywords:
Suggest new keywords:
platelet contamination
Streptococcus bovis
bacterial sepsis
Reference attachment:
Suggest references:
Chang, A.H., Kirsch, C.M., Mobashery, N., Johnson, N. and Levitt, L.J. (2004). Streptococcus bovis septic shock due to contaminated transfused platelets. Am J Hematol 77(3): 282-6.
Expert comments for publication:
Bacterial contamination is now the most common infectious complication of transfusion.