Streptococcus bovis

Status: 
Ready to upload
Record number: 
1333
Adverse Occurrence type: 
MPHO Type: 
Estimated frequency: 
Under dispute but approximately 350/100,000 platelets
Time to detection: 
45 minutes
Alerting signals, symptoms, evidence of occurrence: 
Fever of 40°C, rigors, persistent hypotension unresponsive to fluids, WBC 42,000.
Demonstration of imputability or root cause: 
Culture of Streptococcus bovis in the platelet bag, sealed tubing of platelets, and 4 blood cultures from the recipient.
Imputability grade: 
3 Definite/Certain/Proven
Suggest new keywords: 
platelet contamination
Streptococcus bovis
bacterial sepsis
Reference attachment: 
Suggest references: 
Chang, A.H., Kirsch, C.M., Mobashery, N., Johnson, N. and Levitt, L.J. (2004). Streptococcus bovis septic shock due to contaminated transfused platelets. Am J Hematol 77(3): 282-6.
Expert comments for publication: 
Bacterial contamination is now the most common infectious complication of transfusion.