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Adverse Occurrence type:
100% transmission ocurred in both liver and kidney recipients
Time to detection:
Alerting signals, symptoms, evidence of occurrence:
DONOR: 11-month-old male from a high tuberculosis (TB) incidence country. Cause of death: Dandy Walker syndrome with cerebral infarction. TB was not suspected during the donation process and autopsy was not performed. Chest X ray normal. RECIPIENTS: LIVER: a 4-year-old recipient without history or background of TB developed liver TB (Mycobacterium tuberculosis isolated in gastric fluid), gender not stated. TST not performed, received TB treatment, alive. KIDNEY: a double kidney transplant in a 49 year-old TST negative recipient developed positive PPD skin test. The recipient was treated with isoniazid for 9 months, alive.
Coll et all. Incidence of Tuberculosis in Deceased-Organ Donors and Transmission Risk to Recipients in Spain. Transplantation 2013;96: 205-210.