Mycobacterium tuberculosis

Ready to upload
Record number: 
Adverse Occurrence type: 
MPHO Type: 
Estimated frequency: 
100% transmission ocurred in both liver and kidney recipients
Time to detection: 
2 months
Alerting signals, symptoms, evidence of occurrence: 
DONOR: 11-month-old male from a high tuberculosis (TB) incidence country. Cause of death: Dandy Walker syndrome with cerebral infarction. TB was not suspected during the donation process and autopsy was not performed. Chest X ray normal. RECIPIENTS: LIVER: a 4-year-old recipient without history or background of TB developed liver TB (Mycobacterium tuberculosis isolated in gastric fluid), gender not stated. TST not performed, received TB treatment, alive. KIDNEY: a double kidney transplant in a 49 year-old TST negative recipient developed positive PPD skin test. The recipient was treated with isoniazid for 9 months, alive.
Imputability grade: 
2 Probable
Suggest references: 
Coll et all. Incidence of Tuberculosis in Deceased-Organ Donors and Transmission Risk to Recipients in Spain. Transplantation 2013;96: 205-210.