Status:
Ready to upload
Record number:
1173
Adverse Occurrence type:
MPHO Type:
Estimated frequency:
Rare, but no frequency data available
Time to detection:
2 - 3 days
Alerting signals, symptoms, evidence of occurrence:
Two patients received plasma transfusion from the same donor, both reported periorbital edema, pharyngeal pruritus, and mild dyspnea following eating peanut butter.
Demonstration of imputability or root cause:
Review of the implicated units revealed a common unit number of apheresis plasma. Each recipient had received 1unit of the common source plasma. The donor of the implicated unit reported a history of severe peanut allergy. Transfusion-transmitted atopy.
Imputability grade:
3 Definite/Certain/Proven
Groups audience:
Keywords:
References:
Suggest new keywords:
"Plasma, apheresis, allergy, atopy, transfusion, pruritus, flushing, edema, dyspnea, IgE, anaphylaxis, fluorescent enzyme immunoassay,"
Suggest references:
Poisson, J.L., Riedo, F.X. and AuBuchon, J.P. (2014). Acquired peanut hypersensitivity after transfusion. Transfusion 54(1): 256-7; Savage, W.J., Tobian, A.A.R., Wood, R.A. Schroeder, J.T. and Ness, P.M. (2011). Scratching the surface of allergic transfusion reactions. Transfusion53(6): 1361-71.