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Adverse Occurrence type:
Time to detection:
Alerting signals, symptoms, evidence of occurrence:
Double cord unit 'shocked heart' reaction
Demonstration of imputability or root cause:
Double cord unit 'shocked heart' reaction. It is not reported whether the cord blood units were washed before infusion or if they were volume reduced.
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cord blood, washed,
Expert comments for publication:
The S(P)EAR Committee reviews adverse reaction reports from transplant facilities on an annual basis and determines imputability on reported cases. Cardiogenic shock is defined by sustained low blood pressure with tissue hypoperfusion despite adequate left ventricular filling pressure. Signs of tissue hypoperfusion include oliguria (<30 mL/h), cool extremities, and altered level of consciousness.