Atopy/allergy

Record number: 
1098
Adverse Occurrence type: 
MPHO Type: 
Estimated frequency: 
Known. Not uncommon
Time to detection: 
months - years
Alerting signals, symptoms, evidence of occurrence: 
Food allergy. Asthma. Drug allergy. Rhinitis
Demonstration of imputability or root cause: 
No allergy prior to transplant. Donor has history of atopy/allergy. Raised serum IgE, positive radioallergosorbent tests.
Suggest references: 
Tucker, J, et al 1986. Atopy after bone marrow transplantation. Br Med J 290:116-7; Bellou, A. et al 1997. Transfer of atopy following bone marrow transplantation. Ann Allergy Asthma Immunol 78:513-6; Walker, SA, et al, 1986. Total and allergen-specific IgE in relation to allergic response pattern following bone marrow transplantation. Clin Exp Immunol 66:633-9; Agosti, JM, et al, 1988.Transfer of allergen-specific IgE-mediated hypersensitivity with allogeneic bone marrow transplantation. N Engl J Med 319:1623-8; Khan, f, et al, 2009. Is allergic disease curable or transferable with allogeneic hematopoietic cell transplantation? Blood 113:279-90.