14.4.4 Genetic testing of sample from cancer, e.g. HLA testing

Other strategies applied rely on genetic testing of the cancer compared to that of donor and recipient tissue. Different gene sequences and polymorphysims have been studied in the process of assessing attributability. The origin of the tumor can be identified by microsatellite analysis by Polymerase Chain Reaction (PCR) using different markers. Paternity test by genomic allelotyping investigation is another reliable technique to verify attributability. This test permits the analysis of 16 highly polymorphic loci (with the AmpF/STR identifier PCR amplification kit) for effective discrimination of donor/recipient tumor origin.