Successful treatment of Balamuthia mandrillaris amoebic infection with extensive neurological and cutaneous involvement

TitleSuccessful treatment of Balamuthia mandrillaris amoebic infection with extensive neurological and cutaneous involvement
Publication TypeJournal Article
Year of Publication2010
AuthorsMartinez DY, Seas C, Bravo F, Legua P, Ramos C, Cabello AM, Gotuzzo E
JournalClin Infect Dis
Volume51
Issue2
Paginatione7 - 11
Date PublishedJul 15
ISSN1537-6591 (Electronic) 1058-4838 (Linking)
Accession Number20550438
KeywordsAdult, Aged, Albendazole / therapeutic use, Amebiasis / *drug therapy / *parasitology / pathology, Amoebozoa / classification / *isolation & purification, Antiprotozoal Agents / *therapeutic use, Brain / radiography, Child, Child, Preschool, Encephalitis / *drug therapy / parasitology, Female, Fluconazole / therapeutic use, Histocytochemistry, Humans, Magnetic Resonance Imaging, Male, Middle Aged, Phosphorylcholine / analogs & derivatives / therapeutic use, Skin Diseases, Parasitic / *drug therapy / parasitology / pathology, Treatment Outcome, Young Adult
Abstract

Granulomatous amoebic encephalitis caused by Balamuthia mandrillaris is an uncommon infection for which there is no optimal therapy. We describe a young, female patient who presented with extensive cutaneous and neurological involvement and who recovered after receiving prolonged treatment with miltefosine, fluconazole, and albendazole.

DOI10.1086/653609
Short TitleSuccessful treatment of Balamuthia mandrillaris amoebic infection with extensive neurological and cutaneous involvement
Notify Library Reference ID967

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