Probable Creutzfeldt-Jakob disease after a cadaveric dural graft

TitleProbable Creutzfeldt-Jakob disease after a cadaveric dural graft
Publication TypeJournal Article
Year of Publication1995
AuthorsLang CJ, Schuler P, Engelhardt A, Spring A, Brown P
JournalEur J Epidemiol
Pagination79 - 81
Date PublishedFeb
ISSN0393-2990 (Print) 0393-2990 (Linking)
Accession Number7489777
Keywords*Disease Transmission, Infectious, Adult, Astrocytoma / surgery, Cadaver, Creutzfeldt-Jakob Syndrome / etiology / *transmission, Dura Mater / *transplantation, Electroencephalography, Fatal Outcome, Female, Humans, Iatrogenic Disease, Reoperation, Spinal Cord Neoplasms / surgery, Tissue Transplantation / adverse effects

A 26-year old female who had received a cervical cadaveric dural graft 7 years earlier developed psychotic behavior and generalized myoclonic jerks. Following rapid deterioration and appearance of high-charge sharp periodic waves on electroencephalography she died within two months. We believe that this patient is the first German who acquired Creutzfeldt-Jakob disease by dural implant.

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