Contamination of donor cornea: postpenetrating keratoplasty endophthalmitis

TitleContamination of donor cornea: postpenetrating keratoplasty endophthalmitis
Publication TypeJournal Article
Year of Publication1991
AuthorsAntonios SR, Cameron JA, Badr IA, Habash NR, Cotter JB
Pagination217 - 20
Date PublishedMay
ISSN0277-3740 (Print) 0277-3740 (Linking)
Accession Number2055027
Keywords*Tissue Donors, Adolescent, Adult, Aged, Child, Child, Preschool, Cornea / *microbiology, Endophthalmitis / *microbiology, Eye Infections, Bacterial / *etiology, Eye Infections, Fungal / *etiology, Humans, Incidence, Infant, Infant, Newborn, Keratoplasty, Penetrating / *adverse effects, Retrospective Studies, Risk Factors, Tissue Preservation

Nine cases (0.41%) of bacterial and fungal endophthalmitis developed out of a total of 2,210 consecutive penetrating keratoplasties performed between November 1983 and April 1989. Five of the nine cases (0.23%) had endophthalmitis related to donor tissue contamination. The donor tissue of these cases had a storage time of greater than 5 days. A retrospective analysis of 1,399 consecutive corneoscleral rim cultures showed a contamination rate of 29%. The most common organisms isolated were Propionibacterium 26%, diphtheroids 24%, Staphylococcus epidermidis 22%, and fungi 9%. There is a statistically significant increase (p less than 0.005) in the percentage of contaminated donor rims with a preservation time of more than five days. The risk of developing endophthalmitis is 12 times greater with a positive donor rim culture. Prolonged preservation of donor tissue can be a risk factor in developing endophthalmitis.

URLinternal-pdf://Antonios - contamination of donor corneas-1185220096/Antonios - contamination of donor corneas.pdf
Notify Library Reference ID85

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