Title | Occurrence of multiple myeloma in both donor and recipient after bone marrow transplantation |
Publication Type | Journal Article |
Year of Publication | 2002 |
Authors | Kumar A, Styler MJ, Topolsky DL, Crilley PA, Przybysz TM, Gladstone DE |
Journal | Am J Hematol |
Volume | 71 |
Issue | 3 |
Pagination | 227 - 8 |
Date Published | Nov |
ISSN | 0361-8609 (Print) 0361-8609 (Linking) |
Accession Number | 12410583 |
Keywords | *Tissue Donors, Adult, Bone Marrow Transplantation / *adverse effects, Humans, Leukemia, Myelogenous, Chronic, BCR-ABL Positive / *surgery, Male, Multiple Myeloma / *etiology |
Abstract | The transplantation of malignant cells during allogeneic transplant is a rare occurrence. 27 months after donating progenitor cells, a diagnosis of multiple myeloma was made in a 6/6 HLA-phenotypically matched unrelated donor. The 42-year-old recipient transplanted for chronic phase chronic myeloid leukemia developed IgA myeloma 40 months after transplantation. Serum electrophoresis and bone marrow investigations established the diagnosis of IgA K multiple myeloma in both. This case illustrates the natural history and biology of multiple myeloma. |
DOI | 10.1002/ajh.10239 |
Notify Library Reference ID | 845 |