| Title | Malignant neoplasms following cardiac transplantation |
| Publication Type | Journal Article |
| Year of Publication | 1978 |
| Authors | Krikorian JG, Anderson JL, Bieber CP, Penn I, Stinson EB |
| Journal | Jama |
| Volume | 240 |
| Issue | 7 |
| Pagination | 639 - 43 |
| Date Published | Aug 18 |
| Accession Number | 353312 |
| Keywords | *Heart Transplantation, *Postoperative Complications, Adolescent, Adult, Colonic Neoplasms / etiology, Humans, Immunosuppression / *adverse effects, Leukemia / etiology, Lymphoma / etiology, Middle Aged, Neoplasms / *etiology, Research Support, U.S. Gov't, P.H.S., risk, Skin Neoplasms / etiology, Transplantation, Homologous |
| Abstract | Between Jan 6, 1968, and April 11, 1977, 124 patients underwent cardiac transplantation at Stanford University Medical Center, with a mean and median period of follow-up of 18.3 and 9.7 months, respectively. Malignant neoplasms developed in seven patients--three lymphoproliferative neoplasms, two skin cancers, one acute leukemia, and one colon carcinoma. Visceral tumors were often fatal and caused 11% of deaths after three months following transplantation. The incidence and spectrum of malignant neoplasms in this population are similar to those observed in recipients of renal homografts. |
| Notify Library Reference ID | 836 |
