Emergent lung retransplantation after discovery of two primary malignancies in the donor

TitleEmergent lung retransplantation after discovery of two primary malignancies in the donor
Publication TypeJournal Article
Year of Publication2001
AuthorsKreisel D, Engels FH, Krupnick AS, Szeto WY, Krasinskas AM, Popma SH, Tomaszewski JE, Arcasoy SM, Kotloff RM, Blumenthal NP, Buell JF, Rosengard BR
Pagination1859 - 62
Date PublishedJun 27
ISSN0041-1337 (Print) 0041-1337 (Linking)
Accession Number11455271
Keywords*Emergency Medical Services, *Lung Transplantation, *Tissue Donors, Adult, Aortic Diseases / pathology, Carcinoma, Renal Cell / pathology, Female, Humans, Kidney Neoplasms / pathology, Middle Aged, Neoplasms, Multiple Primary / pathology, Reoperation, Sarcoma / pathology / secondary, Splenic Neoplasms / pathology / secondary

A 50-year-old woman underwent single lung transplantation for advanced chronic obstructive pulmonary disease. Shortly after the procedure, it was discovered that the donor suffered from both a renal cell carcinoma and a spindle-cell sarcoma of the ascending aorta, which had metastasized to the spleen. The patient was emergently listed for a retransplantation and underwent bilateral lung transplantation after a new donor became available 4 days after the initial transplantation procedure. After 24 months, the patient is without evidence of malignancy. This case illustrates the role of immediate retransplantation for patients who have inadvertently received thoracic organs from donors harboring occult malignancies.

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