Candida keratitis after descemet stripping and automated endothelial keratoplasty

TitleCandida keratitis after descemet stripping and automated endothelial keratoplasty
Publication TypeJournal Article
Year of Publication2009
AuthorsKoenig SB, Wirostko WJ, Fish RI, Covert DJ
Pagination471 - 3
Date PublishedMay
ISSN1536-4798 (Electronic) 0277-3740 (Linking)
Accession Number19411972
Keywords*Disease Transmission, Infectious, Aged, 80 and over, Candida albicans / isolation & purification, Candidiasis / microbiology / surgery / *transmission, Cornea / *microbiology, Corneal Transplantation / *adverse effects, Descemet Membrane / surgery, Endothelium, Corneal / *transplantation, Eye Infections, Fungal / microbiology / surgery / *transmission, Female, Humans, Keratitis / *microbiology / surgery, Keratoplasty, Penetrating, Tissue Donors

PURPOSE: To report the donor-to-host transmission of Candida albicans after Descemet stripping and automated endothelial keratoplasty (DSAEK). METHODS: An 80-year-old woman with pseudophakic bullous keratopathy developed an infiltrate in the donor corneal lenticule after DSAEK. RESULTS: Donor corneoscleral rim cultures grew C. albicans. Gram stain of the removed corneal lenticule demonstrated budding yeast and pseudohyphae, and cultures yielded C. albicans. Despite topical and systemic antifungal therapy and therapeutic penetrating keratoplasty, the patient developed a blind painful eye and underwent enucleation. CONCLUSIONS: This case report indicates that fungal keratitis may occur from donor-to-host transmission after DSAEK. The location of the infected tissue poses diagnostic and therapeutic challenges for the surgeon.

URLinternal-pdf://Koenig - Candida_Keratitis_After_Descemet_Stripping-0698382080/Koenig - Candida_Keratitis_After_Descemet_Stripping.pdf
DOI10.1097/ICO.0b013e31818ad9bc 00003226-200905000-00021 [pii]
Notify Library Reference ID814

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