Cytomegalovirus infection in burn patients

TitleCytomegalovirus infection in burn patients
Publication TypeJournal Article
Year of Publication1987
AuthorsKealey GP, Bale JF, Strauss RG, Massanari RM
JournalJ Burn Care Rehabil
Pagination543 - 5
Date PublishedNov-Dec
ISSN0273-8481 (Print) 0273-8481 (Linking)
Accession Number2830289
KeywordsAntibodies, Viral / *analysis, Burns / *complications, Cytomegalovirus Infections / *diagnosis, Humans, Prospective Studies, Risk Factors, Wound Infection / diagnosis / *etiology

We studied the seroepidemiology of cytomegalovirus (CMV) infection in 59 patients with thermal injuries. Among the 31 patients who were initially CMV seronegative, seven (22.5%) seroconverted. Patients who seroconverted had longer hospital stays (mean, 27 +/- 23.9 days v 14.9 +/- 8.8 days in seronegative patients [P = 0.03]) and they received more blood products (mean, 10.7 +/- 17.9 units v 1.8 +/- 2.8 units [P = 0.02]) than patients who remained seronegative. Among 18 patients who were initially seropositive for CMV, 10 (56%) had a fourfold or greater rise in CMV antibodies, evidence of CMV reactivation. Patients who had reactivated CMV infection tended to be younger, to have a larger burn area, and to have a longer hospital stay. No patient who experienced CMV infection, whether primary or reactivated, had serious complications attributable to CMV.

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