[Malignant neoplasms and kidney transplantation]

Title[Malignant neoplasms and kidney transplantation]
Publication TypeJournal Article
Year of Publication2009
AuthorsHeynemann H, Hamza A, Wagner S, Hoda R, Schumann A, Fornara P
JournalUrologe A
Pagination1443 - 51
Date PublishedDec
ISSN1433-0563 (Electronic) 0340-2592 (Linking)
Accession Number19911154
KeywordsCausality, Humans, Incidence, Kidney Transplantation / *utilization, Neoplasm Metastasis, Neoplasms / *epidemiology, Postoperative Complications / *epidemiology, Precancerous Conditions / *epidemiology, Risk Assessment, Tissue Donors / *statistics & numerical data

Together with cardiovascular disorders and metabolic changes, malignant diseases are considered as great challenges in clinical transplantation. As far as long-term function of transplanted organs is concerned, an impact of malignancies is obvious. However, it is important to distinguish between neoplastic disease originating from preexisting lesions in the transplanted organs and de novo graft tumors. Further, there is also a high risk of developing malignant disease during the dialysis, likely due to potential harmful metabolic changes associated with this procedure. After curative management of tumors in such patients, an interval of 2 years for surveillance should be adhered to before patients are put back on the waiting list. The overall risk of transmission of a malignant disease with the transplanted graft has been considered to be as low as

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