The quarantine of fertilized donated oocytes

TitleThe quarantine of fertilized donated oocytes
Publication TypeJournal Article
Year of Publication1995
AuthorsHamer FC, Horne G, Pease EH, Matson PL, Lieberman BA
JournalHum Reprod
Pagination1194 - 6
Date PublishedMay
ISSN0268-1161 (Print) 0268-1161 (Linking)
Accession Number7657764
Keywords*Oocyte Donation, *Quarantine, Adult, Blastocyst, Cryopreservation, Embryo Transfer, Female, Fertilization in Vitro, HIV Infections / prevention & control / transmission, Humans, Pregnancy, Time Factors, Tissue Donors

The fertilization and subsequent cryopreservation of donated oocytes have enabled the resulting embryos to be quarantined for a minimum of 6 months, and to be thawed and replaced only after the donor has had a second negative human immunodeficiency virus (HIV) test. In the study described here, a total of 39 women had 56 embryo transfers, and 12 pregnancies (21% per transfer) were achieved. The logic of the protocol for minimizing the risk of infection of the recipient, which is in line with that of semen donation, is presented, together with an argument for the feasibility of such an approach.

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