Fungal keratitis with intracameral extension following penetrating keratoplasty

TitleFungal keratitis with intracameral extension following penetrating keratoplasty
Publication TypeJournal Article
Year of Publication2009
AuthorsGupta G, Feder RS, Lyon AT
Pagination930 - 2
Date PublishedSep
ISSN1536-4798 (Electronic) 0277-3740 (Linking)
Accession Number19654519
KeywordsAdministration, Oral, Administration, Topical, Anterior Chamber / *pathology, Antifungal Agents / administration & dosage, Aspergillosis / drug therapy / *etiology, Corneal Stroma / surgery, Debridement, Drug Administration Schedule, Graft Rejection / drug therapy, Humans, Injections, Keratitis / *microbiology / *pathology / physiopathology / surgery, Keratoconus / surgery, Keratoplasty, Penetrating / *adverse effects, Male, Middle Aged, Postoperative Care, Prednisolone / administration & dosage, Pyrimidines / administration & dosage, Triazoles / administration & dosage, Visual Acuity

PURPOSE: To report the clinical findings and management of a case of fungal keratitis with extension into the anterior chamber following penetrating keratoplasty. METHODS: Interventional case report. RESULTS: A 45-year-old man developed a white, cottonball-like mass in the anterior chamber 3 months after penetrating keraplasty for keratoconus. Cytology evaluation was performed following excisional biopsy of the intracameral portion of the lesion. The presence of filamentous fungus was confirmed. The patient was treated with oral, topical, and intracameral voriconazole with complete resolution of the infection 9 months after initial presentation. CONCLUSION: This case illustrates the unusual presentation of fungal keratitis with intracameral extension and demonstrates effective management with preservation of the corneal graft and restoration of visual function.

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Notify Library Reference ID617

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