Sarcomatoid renal cell carcinoma in a renal transplant recipient

TitleSarcomatoid renal cell carcinoma in a renal transplant recipient
Publication TypeJournal Article
Year of Publication2009
AuthorsLlamas F, Gallego E, Salinas A, Virseda J, Pérez J, Ortega A, Nam SH, Gómez C
Date PublishedDec

The incidence of transplanted kidneys derived from elderly donors is increasing because of the larger waiting lists and greater age of patients with end-stage renal failure. Compared with young donors, one of the problems is the heightened risk of neoplasm transmission. We report 2 cases of kidney recipients, both of whom developed a sarcomatoid renal cell carcinoma after receiving a kidney transplant from the same 68-year-old male donor, who did not show signs of a neoplasm on a previous abdominal ultrasound or a pretransplant biopsy. The first recipient was a 66-year-old woman who developed a kidney mass with several urologic obstructive complications, tumor dissemination, and death at 9 months after kidney transplantation. The second recipient was a 48-year-old asymptomatic man with normal renal function, who was studied after the results of the first recipient, revealing another renal tumor. Transplant nephrectomy was performed and a peritoneal implant was resected. The patient is alive without evidence of a neoplasm after 18 months. Herein we have discussed the mechanisms of neoplasm transmission in kidney transplantation and possible strategies for its prevention and treatment.

Alternate JournalTransplantation Proceedings
Notify Library Reference ID4879