|Title||A fatal case of West Nile virus infection in a bone marrow transplant recipient|
|Publication Type||Journal Article|
|Year of Publication||2003|
|Authors||Hiatt B, DesJardin L, Carter T, Gingrich R, Thompson C, de Magalhaes-Silverman M|
West Nile virus (WNV) can cause severe, potentially fatal neurological illnesses, which include encephalitis, meningitis, Guillain-Barré syndrome, and anterior myelitis. Because of the short viremic phase, WNV infection is most commonly diagnosed by detection of immunoglobulin M antibody to WNV in serum or cerebrospinal fluid (CSF). We describe a patient with T cell lymphoma who had undergone a T cell-depleted bone marrow transplantation and developed fatal WNV infection. The results of serological tests of blood samples and of CSF tests were negative. Diagnosis was made postmortem by a positive result of reverse-transcriptase polymerase chain reaction (ABI 7700; TaqMan) for WNV in stored CSF and serum samples.
|Alternate Journal||Clin Infect Dis.|
|Notify Library Reference ID||4780|