Sarcomatoid renal cell carcinoma in a renal transplant recipient

TitleSarcomatoid renal cell carcinoma in a renal transplant recipient
Publication TypeJournal Article
Year of Publication2009
Authors, Salinas A, Virseda J, Pérez J, Ortega A, Nam SH, Gómez C
Volume41
Issue10
Pagination22
Date PublishedDec
Abstract

The incidence of transplanted kidneys derived from elderly donors is increasing because of the larger waiting lists and greater age of patients with end-stage renal failure. Compared with young donors, one of the problems is the heightened risk of neoplasm transmission. We report 2 cases of kidney recipients, both of whom developed a sarcomatoid renal cell carcinoma after receiving a kidney transplant from the same 68-year-old male donor, who did not show signs of a neoplasm on a previous abdominal ultrasound or a pretransplant biopsy. The first recipient was a 66-year-old woman who developed a kidney mass with several urologic obstructive complications, tumor dissemination, and death at 9 months after kidney transplantation. The second recipient was a 48-year-old asymptomatic man with normal renal function, who was studied after the results of the first recipient, revealing another renal tumor. Transplant nephrectomy was performed and a peritoneal implant was resected. The patient is alive without evidence of a neoplasm after 18 months. Herein we have discussed the mechanisms of neoplasm transmission in kidney transplantation and possible strategies for its prevention and treatment.

DOI10.1016/j.transproceed.2009.08.066
Alternate JournalTransplant Proc
Notify Library Reference ID4715

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